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Uitenhage police are investigating a case of culpable homicide following a head on colision on the N2 near Wittelsbos, Stormsriver.
Police spokesperson, Warrant Officer Gerda Swart says a horse and trailer and a courier truck collided head on late on Thursday night.
Swart says a 24-year old man from Cape Town traveling to Port Elizabeth passed away at the scene.
She says the other driver sustained slight injuries.