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About 3000 members of the SA Clothing and Textile Workers Union in the cotton sector are on strike.
Sactwu says it issued a strike notice to employers on Monday following failed wage negotiations.
Union general secretary, Andre' Kriel says the issue in dispute is the employers' final wage package increase offer of 7.75%.
He says workers are demanding a 10% wage increase.
At least one Port Elizabeth company in Neave Township is affected by strike action.