Two people were arrested in the early hours of Friday morning after mandrax tablets worth R5 million were found inside their vehicle.
Members of the flying squad were busy with patrols on the N2 when a suspicious-looking Nissan Almera drove past them.
He says members decided to stop and search the vehicle which led to the discovery.
Beetge says there were 50 plastic bags containing about 1 500 mandrax tablets each, which were stacked in the boot of the car.
The total of 77 500 tablets have an estimated street value of R5 million.
The 45-year-old driver and his 26-year-old female passenger were arrested on the spot and will appear in the Alexandria Magistrates Court on Monday.