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Four people have died when the driver of a bakkie lost control and the vehicle overturned at Elliotdale.
Six people were seriously injured in Thursday night's accident, which happened near the Madwaleni-hospital.
Eastern Cape traffic spokesperson Tshepo Machaea says the driver survived the crash -- but disappeared after the accident.
In another accident, a pedestrian was killed late on Sunday afternoon on the R72 between Port Alfred and Kenton on Sea.
Machaea says the driver of the vehicle stopped immediately after the accident and called the police.