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South Africa has suspended imports of Brazilian beef due to mad cow disease.
China and Japan have also halted their imports.
The agriculture ministry in the Brazilian capital, Brasilia, says it has received official notification from China and South Africa over the suspensions.
The ministry said this week that the case was detected in an animal that died in 2010 in the southern state of Parana, adding that it posed no risk whatsoever to public health or to animal hygiene.
With nearly 200 million head of cattle, Brazil is a leading beef exporter.