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World number one and top seed Rafael Nadal will be the leading player in action on Thursday on day five of the French Open at Roland Garros.
The clay-court genius is not expected to have any problems in his second round duel with unseeded Austrian Dominic Thiem.
Wednesday saw the shocking demise of both Williams sisters in round two.
Defending champion and world number one Serena Williams lost 6 2 6 2 to Spain's world number 35 Garbine Muguruza and her sister Venus also went out - 2-6, 6-3, 6-4 to Slovak teenager Anna Schmiedlova.
It was Serena's second-worst defeat ever at Grand Slam level.
Her shock exit, and that of 2nd seed Li Na a day earlier, means that Maria Sharapova is now the overwhelming favourite to lift the ladies crown.
She had her work cut-out in round two, however, and had to overcome difficult conditions to battle past Bulgaria's Tsvetana Pironkova 7-5, 6-2.
There were no problems for third seed Agnieszka Radwanska who reached the third round with a 6-3, 6-4 win over Karolina Pliskova.
Amongst the men; Roger Federer reached the third round with a 6-3, 6-4, 6-4 win over Argentine qualifier Diego Schwartzman.
Novak Djokovic advanced with a routine 6-1, 6-4, 6-2 win over the Frenchman Jeremy Chardy.
There were also 2nd round wins for 6th seed Tomas Berdych, 8th seeded Canadian Milos Roanic and the two Frenchman Gilles Simon and Jo-Wilfred Tsonga
