This article may contain graphic and/or adult content unsuitable for minors and sensitive readers.
Second seed Roger Federer was bundled out of the Australian Open third round by Italian Andreas Seppi on Friday, suffering his first career defeat in 11 meetings between the pair in the 6-4 7-6 4-6 7-6 loss.
The 17-times grand slam champion has not lost this early in the season-opening grand slam since his second trip to Melbourne Park in 2001, when he also lost in the third round.
Sixth seed Andy Murray set up a mouth-watering clash with Grigor Dimitrov and a chance to avenge his quarter final defeat at Wimbledon last year after destroying Portugal's Joao Sousa 6-1 6-1 7-5 to reach the fourth round.
Seventh-seeded Tomas Berdych became the first man to advance to the fourth round with a 6-4, 6-3, 6-4 win over Viktor Troicki of Serbia.
