American Andy Roddick suffered a third-round loss at the Winston-Salem Open in North Carolina on Thursday, losing in straight sets to Belgium's Steve Darcis 7-6 7-6.
Darcis next faces second-seeded Tomas Berdych of the Czech Republic, who advanced with a 6-3, 6-2 win over Finland's Jarkko Nieminen.
The hardcourt tournament serves as a warm-up event for next week's US Open at Flushing Meadows.