Wigan Athletic added to last week's surprise victory over Premier League leaders Manchester United by beating third-place Arsenal 2-1 at the Emirates Stadium Monday night.
Two early goals turned out to be enough for Roberto Martinez's side to pull off the win which significantly improves their chances of avoiding relegation.
The Latics are now five points clear of third-bottom Bolton Wanderers, who have two games in hand, in a five-team tussle to avoid the drop.
The result was a blow to the Gunner's hopes of holding off the challenges of Tottenham and Newcastle and qualify for the Champions League in third place.
