Grey's Anatomy fans will be happy to know that Karev's mother who was first introduced in season 14, will return in season 15.
The role of Helen Karev, a woman who suffers from schizophrenia, is played by 69-year-old actress, Lindsay Wagner.
The back story of the character offers reasons to why Alex Karev cut ties with her.
Young Alex was given the difficult task of taking care of his siblings when his mother failed to feed and take care of them.
Later as a teen, he took care of his mother the primary caregiver, making sure she took her medication to calm her delusions.
Season 15 will offer more insight into their relationship.
With season 15 in play and the contract to season 16 already signed, Grey's Anatomy is officially the longest-running television medical series.