Two suspects are due to appear in court on Monday on charges of human trafficking, after 39 people, including women and children that they allegedly trafficked, were freed by police in Belfast in Mpumalanga.
Police spokesperson, Colonel Katlego Mogale, says their victims included seven women, nine children under the age of five and 27 men.
She said the men were arrested on a farm in the Belfast area on Friday during a multidisciplinary operation, that included officials from the Department of Home Affairs.
Mogale says the Mozambican nationals, who were lured into the country as farm labour, will be kept in a place of safety in Witbank.
She says the modus operandi entails the victims being brought into South Africa in a taxi from Mozambique until Lydenburg where the son of the farm owner and one trafficker will allegedly meet the taxi driver to make payment.
The suspects, both aged 32, will be charged with trafficking in persons.