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A huge methane gas explosion at a mine shaft rocked Welkom in the northern Free State late on Saturday afternoon.
A massive smoke cloud could be seen billowing above the CBD.
Emergency services say many houses in Jan Cilliers Park, Doorn and Sandania had their windows cracked, and ceilings, walls and toilets damaged.
Eye-witnesses say the explosion was felt and heard as far as Riebeeckstad and Odendaalsrus.
Mediclinic Welkom's spokesperson Marisa Pawson confirmed that six patients were admitted to hospital.
The full extent of the damage is not yet known.
